Efficiency Encapsulation of FK506 with New Dual Self‐Assembly Multi‐Hydrophobic‐Core Nanoparticles for Preventing Keratoplasty Rejection (Adv. Healthcare Mater. 21/2023)
نویسندگان
چکیده
Dual Self-Assembly In article number 2203242, Kaihui Nan, Sen Lin, and co-workers, report new multi-hydrophobiccore nanoparticles (MHC-NPs) with high encapsulation capacity for hydrophobic agents. MHC-NPs achieve a maximal tacrolimus (also known as FK506)-loading amount of 18%, which is higher than those previously reported nanocarriers. After being topically administrated, these FK506 exhibit better protective effect against immunotoxicity in the corneal grafts after keratoplasty free commercial eye drop.
منابع مشابه
Effects of the immunosuppressant FK506 on a penetrating keratoplasty rejection model in the rat.
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ژورنال
عنوان ژورنال: Advanced Healthcare Materials
سال: 2023
ISSN: ['2192-2640', '2192-2659']
DOI: https://doi.org/10.1002/adhm.202370120